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NAD de novo biosynthesis I (from aspartate)

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
nicotinic_acid_mononucleotide + ATP + H+ <=> deamido-NAD+ + diphosphate 2.7.7.1 nicotinamide-nucleotide adenylyltransferase
2.7.7.18 nicotinate-nucleotide adenylyltransferase


iminosuccinate + dihydroxyacetone_phosphate <=> quinolinic_acid + H2O + phosphate 2.5.1.72 quinolinate synthase

nicotinic_acid_mononucleotide + diphosphate + CO2 <=> 5-phospho-alpha-D-ribose_1-diphosphate + quinolinic_acid + H+ 2.4.2.19 nicotinate-nucleotide diphosphorylase (carboxylating)

L-aspartate + O2 <=> H+ + iminosuccinate + H2O2 1.4.3.16 L-aspartate oxidase

NH3 + ATP + deamido-NAD+ <=> H+ + AMP + diphosphate + NAD+ 6.3.1.5 NAD+ synthase
6.3.5.1 NAD+ synthase (glutamine-hydrolysing)


ATP + deamido-NAD+ + L-glutamine + H2O <=> H+ + L-glutamate + AMP + diphosphate + NAD+ 6.3.1.5 NAD+ synthase
6.3.5.1 NAD+ synthase (glutamine-hydrolysing)


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